As immune cells in close contact with tumor cells can be considered as the most efficient effector cells to kill tumor cells via ADCC, we focused on the density of intraepithelial FcγRIIIA+ (CD16) immune cells, identified by flow cytometry, i.e., cytotoxic CD8+ T cells, NK cells and granulocytes (corresponding morphologically to TAN). This evidence concerns the gene CD8A and neoplasm.