Patients in the highest tertile (25(OH)D levels >22,4 ng/ml) had lower CCV risk, compared to those in the intermediate or lowest tertile, due to significantly better profiles of BMI, systolic blood pressure, metabolic syndrome, HDL cholesterol, LDL cholesterol, non-HDL cholesterol, triglycerides, glycemia, cQT, CRP, and C3. This evidence concerns the gene CRP and metabolic syndrome.