FOSL1 and glioblastoma: Metalloproteinases like MMP-2/MMP-9 have been reported earlier to be regulated by FRA-1 in several cancers including GBM (Debinski and Gibo, 2005; Adiseshaiah et al., 2008; Kimura et al., 2011; Prywes and Henckels, 2013).