HSD17B13 and steatosis: Another loss-of-function variant in HSD17B13 (rs72613567:TA) was found to be associated with a reduced risk of chronic liver disease, like alcoholic and non-alcoholic chronic liver diseases, reduced risk of progression from steatosis to steatohepatitis, but not simple steatosis, as well as reduced risk of alcoholic and non-alcoholic cirrhosis in allele dose-dependent manner (69) (71),.