Among the coding exons of 466 genes and various genomic regions previously shown to be involved in HCC including TERT promoter, oncogenic fusions and hepatitis B or C virus genomic integrations, we identified a total of 132 somatic mutations across 98 genes (Supplementary Table S2), including 101 single-nucleotide variants (SNVs) and 31 short insertions and deletions (indels). The gene discussed is TERT; the disease is hepatocellular carcinoma.