MAPT and tauopathy: Although, the tau pathology correlates more strongly with neuronal cells, participation of glial activation in tau-induced neurodegeneration and tangle burden has been reported in the Tg4510 (rTg4510) mouse line (model of Tauopathy) overexpressing Chemokine C-C motif ligand (Joly-Amado et al., 2020).