However, in our study, we focused on the role of SLC16A13 in the liver for three reasons: First, the overall aim of the study is to investigate the potential role of SLC16A13 in human metabolic disease; second, human SLC16A13 expression is the highest in the liver, and third, the liver is crucial in glucose and lipid metabolism. This evidence concerns the gene SLC16A13 and metabolic disease.