CHM and Parkinson disease: In cross-sectional analyses, significant associations of SNCA polymorphisms with Unified Parkinson’s Disease Rating Scale (UPDRS) scores were found in two Asian populations for REP1–263 allele carriers (UPDRS III, β 3.921; p = 0.026)34 and rs11931074 (UPDRS II, standardized coefficient (SC) −0.083; p = 0.035; UPDRS III, SC −0.140; p ≤ 0.001)28.