ACVR1 and fibrodysplasia ossificans progressiva: The above findings are consistent with a recent study of Goldhamer’s group, where the authors employed and characterized a transgenic mouse model that recapitulates a rare autosomal-dominant disorder called fibrodysplasia ossificans progressiva (FOP), which results from a single activating mutation in ACVR1; the type I BMP receptor also known as ACVR1/ALK2.