TFRC and central nervous system cancer: Myristoylated transportan, modified with a transferrin receptor-targeting peptide (myr-TP-Tf), encapsulating siRNA showed the targeting of siRNA over BBB; fluorescence images indicated that the siRNA uptake in murine brain endothelioma and a human glioma cell line, and functional gene silencing in “a human glioma cell line as well as in primary murine neurons/astrocytes” [99].