Rare variants of the BCL2 translocation involving the IGK [t(2;18)(p11;q21)] or IGL [t(18;22)(q21;q11)] loci have been reported in follicular lymphoma (FL) [230,231,232,233,234,235] and chronic lymphocytic leukemia (CLL) [145,236,237]. This evidence concerns the gene BCL2 and B-cell chronic lymphocytic leukemia.