Findings were contradictory, probably because of the different type of investigated disease: there was no statistically significant difference between psoriatic patients and healthy controls, but patients with PASI > 10 had lower IgA levels compared with those of patients with PASI < 10, suggesting that patients affected by moderate-to-severe psoriasis might be at high risk of developing microbial infections [27]. This evidence concerns the gene CD79A and psoriasis.