Interestingly, PBMCs from ME/CFS patients showed lower levels in four mitochondrial proteins: PDPR (FC = 0.85), PANK2 (FC = 0.85), ATP5FIE (FC = 0.86), and SLC25A24 (FC = 0.88). This evidence concerns the gene PDPR and myalgic encephalomeyelitis/chronic fatigue syndrome.