TREM2 and Dravet syndrome: To characterise the SP formation, the brain sections from superior frontal gyrus (SFG), mid temporal gyrus (MTG) and hippocampus from DS and control brains (n = 10 in each group, average age between 42 and 70 years) were analysed by IF and imaged with confocal microscopy, using antibodies specific to Aβ42 (6E10), phospho-tau (pTau, with AT8 antibody), hepcidin and TREM2.