TREM2 and Dravet syndrome: We evaluated hepcidin, ferritin, SOD1, S100β, IL-6 and TREM2 expression in serum and post-mortem brain samples to determine the crosstalk between inflammation and iron dysregulation in normal ageing and in DS pathology and to ascertain how these changes in neuroinflammation could play a role in the acceleration of ageing in DS.