While characterizing Transitional B cell (B220+CD93+) subsets T1, T2 and T3 B cells (Figure 4A–C), we noticed a significant increase in the frequency (Figure S3C) as well as the number (Figure 4F) of Transitional T3 B cells (B220+CD93+IgM+CD23+) from the splenocytes of SbR-BHU138 (drug-resistant strain) infected mice compared to uninfected control mice and infection with drug-sensitive (SbS-AG83) strains. The gene discussed is FCER2; the disease is infection.