Interestingly, the RSV cellular entry mediators in the viral infection are mainly the HSPG, in such a way that it allows us to hypothesize that the RSV inhibition demonstrated by the G2-S16 dendrimer could be due to the interaction of the dendrimer with HSPG of the cellular surface, blocking this crucial initial step of the RSV infection. Here, HSPG2 is linked to viral infectious disease.