CNGB1 and acute lymphoblastic leukemia: The VUS c.2305-34G > A was located 34 bp upstream of exon 24 in the 23rd intron of CNGB1. This variant was known as gnomAD (2.1) and dbSNP (rs370223084) with frequencies reported at 0.0097% (ALL) and 0.0001%, respectively.