Indeed, a large number of cytokines were measurable only in ALS fecal samples (MIP-1α, IL-27, IL-6, MCP-1, P-selectin, IL-1α, IL-18, IL-21, IL-22, sICAM1, E selectin) and, as previously mentioned, IL-2 was significantly higher in patients than controls. This evidence concerns the gene CCL2 and amyotrophic lateral sclerosis.