CXCL8 and pulmonary emphysema: IL-17 may induce the secretion of CXCL8, CXCL1, CXCL5, G-CSF, and GM-CSF from airway epithelial cells, which recruit neutrophils; thus, they may also be related to airway obstruction, emphysema, and even lung cancer development (chronic inflammation) via ROS production and tissue damage (Figure 1) [177,178,179].