According to Chmielewski et al. [64], the spectrum of MM encompasses adipokines, advanced glycation end products (AGEs), appetite regulators, natriuretic peptides, β2-microglobulin (β2-M), complement factor D, cystatin C, endothelin-1, free immunoglobulin light chains, interleukins (IL), parathyroid hormone (PTH), fibroblast growth factor-23 (FGF-23), pentraxin-3, prolactin and retinol-binding protein (RBP). This evidence concerns the gene B2M and Miyoshi myopathy.