The peritoneal fluid (PF) of endometriosis patients was also described to have elevated concentration of proangiogenic factors, such as angiogenin, epithelial-neutrophil-activating peptide (ENA-78), erythropoietin, HGF, IGF-1, and VEGF, and a reduced concentration of antiangiogenic factors, adiponectin, IP-10 (CXCL10), and sVEGFR, which all together favor endometrial lesion development [184,185,186]. This evidence concerns the gene CXCL10 and endometriosis.