KDM6B and myelodysplastic syndrome: In particular, JMJD3 plays an oncogenic role in various tumors such as cancer of the kidneys, breast, prostate, skin, hematopoietic system, melanoma, Hodgkin’s lymphoma (HL), myelodysplastic syndrome (MDS), esophageal squamous cell carcinoma, and ovarian cancer [74].