CCL2 and gastroenteritis: Moreover, these anti-inflammatory effects of AC treatment were additionally observed in extra-intestinal tissues as indicated by lowered nitric oxide and IL-6 concentrations measured in liver, kidney, lungs, and strikingly, also systemically given nitric oxide and MCP-1 concentrations in spleen and serum samples, respectively, that did not differ from basal levels when taken from AC as opposed to placebo-treated mice on day 6 p.i. To date, information on the clinical effects of AC in experimental in vivo models of intestinal inflammation are scarce, however.