MTOR and alkaline phosphatase measurement: Our results also suggest that Rapamycin (a selective mTORC1 inhibitor), but not Torin-2 (a non-selective mTORC1/C2 inhibitor) or FK-506 (which has an impact on oxidative stress in a mTOR-independent manner), could have protective effects against the ethanol-induced LPO and AP site levels in the hippocampus and prefrontal cortex.