ENSG00000236543 and tuberculosis: Genome engineering in the bovine is majorly focused on subjects such as disease resistance (e.g., tuberculosis), eradicating allergens (e.g., beta-lactoglobulin knock-out), product generation (e.g., meat from male and milk from female), male or female birth specifically (animal sexing), the introduction of desirable phenotypes (e.g., stress tolerance, disease resistance) and their long-term survival (e.g., polled or hornlessness) [99].