The results showed that the CFCS ethyl acetate extract has potential cytotoxic activities against both cell lines with higher activity against Caco2 (CD50 14 μg/mL) than Hela cell line (CD50 20 μg/mL), which indicates the presence of metabolites with higher selectivity to human colorectal adenocarcinoma (Table 1). This evidence concerns the gene ICAM3 and colorectal adenocarcinoma.