Besides the observed vascular PSMA expression in the vast majority of GBMs and the shorter survival times in patients with, compared to patients without, vascular PSMA expression, vascular PSMA staining was more frequently seen in IDH1-R132H wild-type gliomas, which are commonly known for having a worse prognosis than IDH1-R132H mutated ones [48]. Here, IDH1 is linked to central nervous system cancer.