Nonetheless, we validated the relationship between the GCH score and the transcriptomic consequences of manipulating the gene expression by stably transfecting DDX19B, NEMP1, PANK2, and UBALD1 on the papillary (BCPAP) and anaplastic (850C) human thyroid cancer cell lines [51,53]. The gene discussed is PANK2; the disease is thyroid gland carcinoma.