Reduced CerK protein and mRNA levels and increased atrogin-1/MAFbx expression also occurred when C2C12 myotubes were incubated with the conditioned medium (CM) obtained from LLC or C26 cells (Figure 3G–L) [32,33,34,35], closely resembling the pattern of the SkM of tumor hosts (see above). This evidence concerns the gene FBXO32 and neoplasm.