TNF and uveitis: In patients with active chronic, anterior uveitis who do not respond well and/or develop complications to topical corticosteroid therapy, particularly in case of ocular hypertonia deserving quick, effective control of inflammation and minimal usage of corticosteroids, it might be worth discussing the early introduction of anti-TNF antibody treatment in association with MTX to control uveitis as quickly as possible, using an expert-center driven treat-to-target approach, an approach that is now encouraged in the treatment of JIA patients [20].