Franco-Martinez et al. [211] identified a total of 169 proteins in the blood proteome of dogs with leishmanial infection; C8 alpha chain, adiponectin, transferrin, sphingomyelin phosphodiesterase acid-like 3A and immunoglobulins showed different modulation between the stages of the infection and could be considered and further validated for the early diagnosis of the infection. This evidence concerns the gene CDCA3 and infection.