Furthermore, we found indication that a glycine-rich peptide, a Kazal-type protease inhibitor and a chitin-binding protein may be involved in response to a β-1,3,-glucan and thus a fungal infection, and also that the clotting protein, α2M and βGBP are likely to bind to cell surfaces as a response to injection of a β-1,3,-glucan and likely helps in an encapsulation reaction. This evidence concerns the gene A2M and fungal infectious disease.