We found that infections with HR HPVs did not depend on the form of TB infection (pulmonary versus extrapulmonary forms), but noted frequent infections with HR HPVs other than HPV 16 among WLWH with generalized TB, and/or low CD4+ T cell counts; specifically, those receiving combined ART/TB therapy, and in general, in WLWH on ART irrespective of their TB status. Here, CD4 is linked to infection.