Seventeen somatic mutations in 11 genes (AR, ASXL1, IFG1R, MAP3K13, PDGFRB, PIK3R1, PTPN11, RICTOR, SNCAIP, SPEN, and SUFU) were restrictively detected in captured CTCs, but not in the corresponding tumor samples (Figure 3 and Table 3). The gene discussed is PIK3R1; the disease is neoplasm.