It was also observed 1,25(OH)2D3 or vitamin D analog regulated mRNA expression of several BMP forms i.e., BMP6 in primary prostate cancer cells [121], BMP2 and BMP6 in MCF10AT1 cells [160], and TGFβ1 and BMP2A in squamous cell carcinoma lines [162]. This evidence concerns the gene BMP6 and Familial prostate cancer.