In conditions of excessive lung stretch, animal models have shown different signaling pathways involved in the induction of pulmonary fibrosis through mechanical transduction, including Rho/rho associated protein kinase (ROCK), myocardin-related transcription factor-A (MRTF-A), and yes-associated protein 1 (YAP)/(transcriptional coactivator with PDZ-binding motif) TAZ signaling pathways [6]. The gene discussed is MRTFA; the disease is pulmonary fibrosis.