Regarding the adipose tissue, the supplementation with an açai seed extract (rich in catechin, epicatechin and polymeric proanthocyanidins) improved the insulin sensitivity and reduced plasma glucose and lipid levels in type 2 diabetic animals together with an increase in p-AKT and GLUT-4 expression both in muscle and adipose tissue [47]. The gene discussed is AKT1; the disease is type 2 diabetes mellitus.