Similarly, in HFD fed mice receiving 50 mg/kg baicalin daily, AKT/AS160/GLUT-4 and p38/PGC-1α/GLUT-4 pathways were stimulated, and contributed to reverse the insulin resistance, insulin intolerance and hyperglycemia in the skeletal muscle [81]. The gene discussed is SLC2A4; the disease is Hyperglycemia.