With the presence of numerous binding sites, ABCB1 and ABCC1 can bind to and pump out a variety of chemotherapeutic drugs, such as Dox in breast cancer; paclitaxel and olaparib in ovarian cancer; and imatinib in chronic myelogenous leukemia [59,60,61]. The gene discussed is ABCB1; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.