Although LKB1 protein expression did not correlate with HER2 status, high LKB1 expression in HER2-positive breast cancer patients correlated with improved overall survival, consistent with the findings of Andrade-Vieira et al. [77] that found NIC mice expressing LKB1 had an increased tumor latency compared to Lkb1−/−NIC mice. This evidence concerns the gene ERBB2 and breast carcinoma.