Recently, more NET-associated markers have been linked to SLE, such is the case of cell-free DNA (cfDNA), myeloperoxidase activity (MPO) and anti-MPO antibodies, which have been found to be higher in SLE patients, which may be useful to better understand the SLE pathogenesis and the development of new therapies [145]. This evidence concerns the gene MPO and systemic lupus erythematosus.