Similarly, 100 ng α-helical CRF microinfused into both LCs rescued undernourished rats from hypertension and tachycardia (Figure 4C,D, #p < 0.05, intergroup comparisons using two-way repeated measures ANOVA followed by Bonferroni’s multiple comparisons test, n = six rats in each group) and allowed the rats to recover responsiveness to phenylephrine administration into the complementary PVN nucleus. The gene discussed is CRH; the disease is hypertensive disorder.