Based on this, probiotic strains that could or could not decrease IL-17 levels in other animal pathological models, including mice with asthma [29], constipation, and rheumatoid arthritis (as measured in other experiments, some data are not shown) were selected and applied to IMQ-induced psoriasis-like mice to compare the ameliorating effects of the strain on psoriasis. This evidence concerns the gene IL17A and rheumatoid arthritis.