There was a significant two-way interaction between the subgroup of Q5 and vitamin D supplementation (p for interaction = 0.04), even on multivariate adjustment with (1) age, (2) sex, (3) body mass index, (4) cancer sites, i.e., esophageal, gastric, and small intestinal plus colorectal cancers, (5) stage, (6) adjuvant chemotherapy, and (7) p53 positivity (p for interaction = 0.02). Here, TP53 is linked to colorectal cancer.