The fusion of FGFR1 with the centrosomal protein 110 (CEP110) drives expansion of the hematopoietic stem cell population, and causes malignancies that frequently turn into AML [221,228,229,230,231,232,233,234,235,236,237,238,239,240,241,242,243,244,245,246,247,248] (Table 1). Here, FGFR1 is linked to acute myeloid leukemia.