PLK1 and cancer: Several mitotic kinases, Aurora A [7,8], polo-like kinase 1 (PLK1) [9] and NIMA-related kinase 2 (NEK2) [10], were shown to block assembly and induce disassembly of the primary cilium, and upregulated activity of these kinases is frequently found in cancer [11,12,13,14,15,16,17,18,19].