Gene fusion involving FGFR3 and the transforming acidic coiled-coil containing protein 3 (TACC3) is one of the recurrent gene fusions, found in glioblastoma (29 of 103), non-small-cell lung carcinoma (28 of 103), head and neck squamous cell carcinoma (11 of 103), bladder cancer (10 of 103), and other types of cancer (Table 1) [133,149,153,179,185,186,187,188,189,190,191,192,193,194,195,196,197,198,199,200]. The gene discussed is TACC3; the disease is cancer.