KCNH2 and cardiac arrhythmia: For instance, verapamil and ranolazines are examples of drugs that are strong inhibitors of the hERG channel and are simultaneously devoid of the risk of inducing arrhythmias and, vice versa, devoid of serious disorders of cardiomyocyte electrophysiology caused by drugs that are weak hERG inhibitors (e.g., sotalol and alfuzosin) [24,69].