Nitzschke et al. showed no significant difference in hormonal parameters in HL patients with and without GnRHa cotreatment: the mean FSH serum levels were 14.7 (SD 6.6) and 14.5 U/L (SD 0.9), respectively, significantly higher compared to healthy women of a control group (5.3 U/L ± SD 1.8); the mean AMH levels were 1.6 (SD 1.4) and 1.4 ng/mL (SD 1.1), respectively, significantly lower than in healthy women (3.9 ng/mL ± SD 1.2) [42]. This evidence concerns the gene BRD2 and Hodgkins lymphoma.