After ABVD, the rate of azoospermia ranged from 0% to 8%; after ABVD and radiotherapy on pelvic nodes, azoospermia was reported in 2% to 11% of patients, whereas after eBEACOPP, abnormal sperm or an increase in serum FSH levels were observed in 90% to 100% of cases. Here, BRD2 is linked to Azoospermia.