CTBP1 and cancer: Chronic stress stimulates activity of the hypothalamic–pituitary axis (HPA) and the sympathetic nervous system (SNS), resulting in the release of norepinephrine (NE) from sympathetic nerve terminals and the stimulation of post-synaptic β-adrenergic receptors (βARs) on target cells, including bone [50] and cancer cells [51,52,53,54,55,56,57] (reviewed in [58]).