EGFR and head and neck squamous cell carcinoma: Nimotuzumab is a humanized IgG1 monoclonal anti-EGFR antibody that has been approved for the following cancer types: (1) squamous cell carcinoma of the head and neck (SCCHN) in India, Cuba, Argentina, Colombia, Ivory Coast, Gabon, Ukraine, Peru, and Sri Lanka; (2) pediatric and adult glioma in Cuba, Argentina, Philippines, and Ukraine; (3) nasopharyngeal cancer in China [45].