BCR and hematologic disorder: In hematological malignancies, MUC1-C has been associated with various pathways related to disease pathogenesis, such as Wnt/β-catenin, fms-like tyrosine kinase 3 (FLT3), breakpoint cluster region protein (BCR)/Tyrosine-protein kinase (ABL), and NF-κB, which are involved in tumorigenesis [26].