Like the other m6A-eraser protein FTO [51], high expression of ALKBH5 has been reported in various subtypes of AML cells carrying t(15;17), Inv(16), t(8;21) and t(11q23) mutations, independent of specific TP53-mutation (in MONOMAC-6/MMC6, NOMO1, and NB4) and TP53-wild type (in MA9.3-ITD and MOLM13) human cell lines [52]. This evidence concerns the gene METTL3 and acute myeloid leukemia.