Among these, the m6A-writer proteins Mettl3 and Mettl14 have been found to be aberrantly expressed in specific subtypes of AML and promotes leukemogenesis by regulating MYB, MYC, Bcl2, pTEN, and PI3K-AKT pathways [43,44,49,118]. The gene discussed is METTL14; the disease is acute myeloid leukemia.