FTO is aberrantly expressed in a specific subset of hematopoietic stem/progenitor cells (HSPCs/CD34+ CD38−) carrying t(11q23)/MLL-rearrangement and t(15;17)/PML-RARA mutations, called acute promyelocytic leukaemia (APL) [51]. This evidence concerns the gene RARA and acute promyelocytic leukemia.