Shen et al., 2020 [52] have demonstrated the role of the other m6A-eraser protein α-ketoglutarate-dependent dioxygenase AlkB homolog 5′ (ALKBH5) in facilitating leukaemia stem/initiating cells (LSCs/LICs) progression, a subset of AML characterized by high self-renewal capacity. This evidence concerns the gene ALKBH5 and acute myeloid leukemia.